Kendamil vs Similac: Complete Formula Comparison 2026

European whole milk formula vs American standard—which is better for your baby?

Quick Summary

Choose Kendamil if: You want whole milk ingredients, no palm oil, European quality, and can afford the premium price.

Choose Similac if: You need wide availability, lower cost, HMO prebiotics, and established pediatrician support.

Choosing between Kendamil and Similac is one of the most common decisions new parents face. Both are reputable formula brands, but they represent fundamentally different approaches to infant nutrition—Kendamil with its European whole milk philosophy and Similac with decades of American medical research backing.

In this comprehensive comparison, we analyze ingredients, nutrition, price, availability, and real-world performance to help you make the right choice for your family.

Quick Comparison Overview

Category Kendamil Similac
Origin United Kingdom United States
Primary Base Whole milk Skim milk powder
Palm Oil No palm oil ✓ Contains palm oil
Price Range $35-45/container $25-35/container
US Availability Limited (growing) Widely available
HMO Prebiotics No (uses GOS) Yes (2'-FL HMO)
Organic Option Yes Yes

Ingredient Deep Dive

Kendamil Ingredients (Stage 1)

  • Milk Base: Whole milk (not skim milk powder)
  • Fats: Coconut oil, sunflower oil, rapeseed oil—no palm oil
  • Carbohydrates: Lactose only (no corn syrup)
  • DHA/ARA: From marine algae (vegetarian)
  • Prebiotics: GOS (galacto-oligosaccharides)

Similac Ingredients (Pro-Advance)

  • Milk Base: Nonfat milk powder
  • Fats: High oleic safflower oil, soy oil, coconut oil, palm oil
  • Carbohydrates: Lactose, corn syrup solids
  • DHA/ARA: From C. cohnii and M. alpina oils
  • Prebiotics: 2'-FL HMO (Human Milk Oligosaccharide)

Key Differences

  • Palm Oil: Kendamil has none; Similac contains palm oil which some research links to harder stools and reduced calcium absorption.
  • Milk Base: Kendamil's whole milk naturally contains MFGM (milk fat globule membrane), important for brain development.
  • Corn Syrup: Similac includes corn syrup solids; Kendamil uses only lactose as the carbohydrate source.
  • HMO: Similac Pro-Advance includes 2'-FL HMO for immune support; Kendamil uses GOS prebiotics instead.

Nutritional Profile

Nutrient (per 100ml) Kendamil Stage 1 Similac Pro-Advance
Energy (kcal) 67 68
Protein (g) 1.4 1.4
Fat (g) 3.6 3.7
Carbohydrates (g) 7.2 7.3
DHA (mg) 17 17
ARA (mg) 17 34
Iron (mg) 0.8 1.2

Both formulas meet FDA and European standards for infant nutrition. The macronutrient profiles are nearly identical. Notable differences: Similac has higher ARA (34mg vs 17mg) and iron content (1.2mg vs 0.8mg).

Cost & Value Analysis

Cost Factor Kendamil Similac
Container Price $35-45 $25-35
Cost per Ounce ~$1.40 ~$1.00
Monthly Cost (newborn) $300-360 $210-270
Annual Difference ~$1,000-1,400 more for Kendamil

Budget Considerations

  • Similac: More affordable, frequent sales/coupons available, often covered by WIC and insurance
  • Kendamil: Premium pricing reflects whole milk ingredients and European manufacturing

Availability

Kendamil

  • In-Store: Limited—some Target and Whole Foods locations
  • Online: Amazon, Kendamil USA website, specialty retailers
  • Stock: Occasional supply limitations
  • Tip: Keep a backup formula option available

Similac

  • In-Store: Available everywhere—pharmacies, grocery stores, Target, Walmart, Costco
  • Online: All major retailers, same-day delivery options
  • Stock: Generally reliable supply
  • Emergency: Available 24/7 at many locations

Winner: Similac. If you're worried about running out of formula at 2 AM, Similac's ubiquity provides peace of mind that Kendamil can't match in the US market.

Final Recommendation

Choose Kendamil If:

  • You prioritize whole milk and cleaner ingredients
  • You want to avoid palm oil (constipation concerns)
  • You prefer European manufacturing standards
  • Budget allows for premium pricing ($90-120 more/month)
  • Your baby seems sensitive to other formulas

Choose Similac If:

  • Budget is a primary consideration
  • You need maximum availability and convenience
  • Your pediatrician specifically recommends it
  • You're covered by WIC or insurance
  • You want HMO prebiotics for immune support

Important Reminder

Both formulas are nutritionally complete and FDA-regulated. The "best" formula is the one your baby tolerates well, fits your budget, and you can reliably access. Always consult your pediatrician before switching formulas.